The Framework for Data Curation (FDC) aims to enable researchers to annotate the meta information of datasets in the GEO and ArrayExpress databases to enable automatic algorithmic analysis. Focusing on a research topic, users can input a query result, composing a list of dataset IDs, downloaded from the GEO and ArrayExpress databases. The server will download the meta information of uploaded dataset IDs. Then, curators will annotate the meta-information based on a set of pre-defined schemes. The annotated sample information will be combined with the processed data matrices from GEO and ArrayExpress databases to enable algorithmic analysis.